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Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody
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Catalog No. TMAB-11186
Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKD3 (Ser41). Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody
Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody
😃Good
Catalog No. TMAB-11186
Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKD3 (Ser41). Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKD3 (Ser41). Anti-Phospho-PRKD3 (Ser41) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Cow,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Membrane. Note=Translocation to the cell membrane is required for kinase activation. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Protein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human PRKD3 around the phosphorylation site of Ser41 |
| Antigen Species | Human |
| Gene Name | PRKD3 |
| Gene ID | |
| Protein Name | Serine/threonine-protein kinase D3 |
| Uniprot ID | |
| Function | Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress. |
| Molecular Weight | Theoretical: 100 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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