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Anti-Spectrin (alpha+beta) Polyclonal Antibody

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Catalog No. TMAB-13098

Anti-Spectrin (alpha+beta) Polyclonal Antibody is a Rabbit antibody targeting Spectrin (alpha+beta). Anti-Spectrin (alpha+beta) Polyclonal Antibody can be used in WB.

Anti-Spectrin (alpha+beta) Polyclonal Antibody

Anti-Spectrin (alpha+beta) Polyclonal Antibody

😃Good
Catalog No. TMAB-13098
Anti-Spectrin (alpha+beta) Polyclonal Antibody is a Rabbit antibody targeting Spectrin (alpha+beta). Anti-Spectrin (alpha+beta) Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Spectrin (alpha+beta) Polyclonal Antibody is a Rabbit antibody targeting Spectrin (alpha+beta). Anti-Spectrin (alpha+beta) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Pig,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytoskeleton. Cytoplasm, cell cortex.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSpectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: Human Spectrin alpha chain, erythrocytic 1
Antigen Species
Human
Gene Name
SPTA1
Gene ID
Protein Name
Spectrin alpha chain, erythrocytic 1
Uniprot ID
Function
Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.
Chemical Properties
Molecular WeightTheoretical: 280 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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