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Anti-MNX1/HLXB9 Polyclonal Antibody 3
😃Good
Catalog No. TMAB-08891
Anti-MNX1/HLXB9 Polyclonal Antibody 3 is a Rabbit antibody targeting MNX1/HLXB9. Anti-MNX1/HLXB9 Polyclonal Antibody 3 can be used in WB.
Anti-MNX1/HLXB9 Polyclonal Antibody 3
Anti-MNX1/HLXB9 Polyclonal Antibody 3
😃Good
Catalog No. TMAB-08891
Anti-MNX1/HLXB9 Polyclonal Antibody 3 is a Rabbit antibody targeting MNX1/HLXB9. Anti-MNX1/HLXB9 Polyclonal Antibody 3 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MNX1/HLXB9 Polyclonal Antibody 3 is a Rabbit antibody targeting MNX1/HLXB9. Anti-MNX1/HLXB9 Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Cow,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in lymphoid and pancreatic tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The HB9 homeobox transcription factor regulates gene expression during embryonic development and also in specific adult tissues. HB9 gene mutations are implicated in Curriano syndrome, which is characterized by a triad consisting of a presacral tumor, sacral agenesis and anorectal malformation. In human bone marrow cells, HB9 expression directly correlates with CD34 expression. Furthermore, HB9 expression increases in CD34+ cells that are treated with IL-3 and granulocyte macrophage-colony-stimulating factor. Early in murine development, HB9 is expressed in pancreatic buds (dorsal and ventral) with subsequent expression in differentiating beta cells in the islets of Langerhans. The dorsal lobe of the pancreas fails to form in HB9(-) mice; the resultant pancreas has smaller islets of Langerhans and less beta cells than normal pancreas. The HB9 gene is expressed in the human adult pancreas. In the developing vertebrate embryo, the HB9 gene plays an essential role in motor neuron differentiation. The motor columns of HB9(-) mice are disorganized, lacking phrenic and abducens nerves and exhibiting intercostal nerve defects. |
| Immunogen | KLH conjugated synthetic peptide: human MNX1/HLXB9 |
| Antigen Species | Human |
| Gene Name | MNX1 |
| Gene ID | |
| Protein Name | Motor neuron and pancreas homeobox protein 1 |
| Uniprot ID | |
| Function | Putative transcription factor involved in pancreas development and function. |
| Molecular Weight | Theoretical: 41 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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