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Anti-DEPTOR Polyclonal Antibody 3

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Catalog No. TMAB-05090

Anti-DEPTOR Polyclonal Antibody 3 is a Rabbit antibody targeting DEPTOR. Anti-DEPTOR Polyclonal Antibody 3 can be used in WB.

Anti-DEPTOR Polyclonal Antibody 3

Anti-DEPTOR Polyclonal Antibody 3

😃Good
Catalog No. TMAB-05090
Anti-DEPTOR Polyclonal Antibody 3 is a Rabbit antibody targeting DEPTOR. Anti-DEPTOR Polyclonal Antibody 3 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-DEPTOR Polyclonal Antibody 3 is a Rabbit antibody targeting DEPTOR. Anti-DEPTOR Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DEPTOR
Antigen Species
Human
Gene Name
DEPTOR
Gene ID
Protein Name
DEP domain-containing mTOR-interacting protein
Uniprot ID
Function
Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.
Chemical Properties
Molecular WeightTheoretical: 46 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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