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Anti-TGF beta Receptor III Polyclonal Antibody
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Catalog No. TMAB-13497
Anti-TGF beta Receptor III Polyclonal Antibody is a Rabbit antibody targeting TGF beta Receptor III. Anti-TGF beta Receptor III Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-TGF beta Receptor III Polyclonal Antibody
Anti-TGF beta Receptor III Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-13497
Anti-TGF beta Receptor III Polyclonal Antibody is a Rabbit antibody targeting TGF beta Receptor III. Anti-TGF beta Receptor III Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-TGF beta Receptor III Polyclonal Antibody is a Rabbit antibody targeting TGF beta Receptor III. Anti-TGF beta Receptor III Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Sheep) |
| Verified Activity | 1. Independently Validated Antibody, image provided by Science Direct, badge number 029661:Formalin-fixed and paraffin embedded human kidney labeled with Anti-TGF Beta R3 Polyclonal Antibody, Unconjugated (TMAB-13497) at 1: 250. overnight at 25C followed by conjugation to the secondary antibody and DAB staining 2. Sample: K562 Cell (Human) Lysate at 40 μg HepG2 Cell (Human) Lysate at 40 μg Hela Cell (Human) Lysate at 40 μg Primary: Anti-TGF beta Receptor III (TMAB-13497) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 94 kD Observed band size: 110 kD 3. Sample: Lane 1: Mouse Placenta tissue lysates Lane 2: Mouse Testis tissue lysates Lane 3: Rat Placenta tissue lysates Lane 4: Rat Testis tissue lysates Lane 5: Human HepG2 cell lysates Lane 6: Human HeLa cell lysates Lane 7: Human A431 cell lysates Primary: Anti-TGF beta Receptor III (TMAB-13497) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 94 kDa Observed band size: 130 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]. |
| Immunogen | KLH conjugated synthetic peptide: human TGFBR3 |
| Antigen Species | Human |
| Gene Name | TGFBR3 |
| Gene ID | |
| Protein Name | Transforming growth factor beta receptor type 3 |
| Uniprot ID | |
| Function | Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. |
| Molecular Weight | Theoretical: 94 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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