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Anti-NFAM1 Polyclonal Antibody
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Catalog No. TMAB-09424 Copy Product Info
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Anti-NFAM1 Polyclonal Antibody is a Rabbit antibody targeting NFAM1. Anti-NFAM1 Polyclonal Antibody can be used in FCM.
Anti-NFAM1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-NFAM1 Polyclonal Antibody is a Rabbit antibody targeting NFAM1. Anti-NFAM1 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Horse) |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Note=Partially recruited to lipid rafts upon BCR stimulation. |
| Tissue Specificity | Highly expressed in neutrophils, primary monocytes, mast cells, monocytic cell lines and lymphocytes. Also expressed in spleen B and T cells, and lung. Expressed at low level in non-immune tissue. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | NFAM1 activates cytokine gene promoters such as the IL13 and TNF-alpha promoters. It contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells. |
| Immunogen | KLH conjugated synthetic peptide: human NFAM1 |
| Antigen Species | Human |
| Gene Name | NFAM1 |
| Gene ID | |
| Protein Name | NFAT activation molecule 1 |
| Uniprot ID | |
| Function | May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking. |
| Molecular Weight | Theoretical: 30 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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