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Anti-PPP1R11 Polyclonal Antibody

Catalog No. TMAB-11675 Copy Product Info
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Anti-PPP1R11 Polyclonal Antibody is a Rabbit antibody targeting PPP1R11. Anti-PPP1R11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-PPP1R11 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-11675

Anti-PPP1R11 Polyclonal Antibody is a Rabbit antibody targeting PPP1R11. Anti-PPP1R11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-PPP1R11 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PPP1R11 Polyclonal Antibody is a Rabbit antibody targeting PPP1R11. Anti-PPP1R11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Rabbit,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat stomach tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (PPP1R11) Polyclonal Antibody, Unconjugated (TMAB-11675) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion.
Tissue SpecificityWidely expressed.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundChromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The KIAA0391 gene product has been provisionally designated KIAA0391 pending further characterization.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PPP1R11
Antigen Species
Human
Gene Name
PPP1R11
Gene ID
9692
Protein Name
E3 ubiquitin-protein ligase PPP1R11
Uniprot ID
O15091
Function
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends.
Chemical Properties
Molecular WeightTheoretical: 14 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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