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Anti-CHML Polyclonal Antibody

Catalog No. TMAB-04308 Copy Product Info
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Anti-CHML Polyclonal Antibody is a Rabbit antibody targeting CHML. Anti-CHML Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CHML Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-04308

Anti-CHML Polyclonal Antibody is a Rabbit antibody targeting CHML. Anti-CHML Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CHML Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CHML Polyclonal Antibody is a Rabbit antibody targeting CHML. Anti-CHML Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CHML) Polyclonal Antibody, Unconjugated (TMAB-04308) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CHML
Antigen Species
Human
Gene Name
CHML
Gene ID
Protein Name
Rab proteins geranylgeranyltransferase component A 2
Uniprot ID
Function
Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than REP-1 in supporting prenylation of Rab3 family.
Chemical Properties
Molecular WeightTheoretical: 74 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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