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Anti-HMGA2 Polyclonal Antibody

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Catalog No. TMAB-07181

Anti-HMGA2 Polyclonal Antibody is a Rabbit antibody targeting HMGA2. Anti-HMGA2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-HMGA2 Polyclonal Antibody

Anti-HMGA2 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-07181
Anti-HMGA2 Polyclonal Antibody is a Rabbit antibody targeting HMGA2. Anti-HMGA2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HMGA2 Polyclonal Antibody is a Rabbit antibody targeting HMGA2. Anti-HMGA2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken)
Verified Activity
Tissue/cell: human ovary carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-HMGA2 Polyclonal Antibody, Unconjugated (TMAB-07181) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HMGA2
Antigen Species
Human
Gene Name
HMGA2
Gene ID
Protein Name
High mobility group protein HMGI-C
Uniprot ID
Function
Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2.
Chemical Properties
Molecular WeightTheoretical: 12 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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