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Anti-KIF5A/NKHC1 Polyclonal Antibody

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Catalog No. TMAB-08050

Anti-KIF5A/NKHC1 Polyclonal Antibody is a Rabbit antibody targeting KIF5A/NKHC1. Anti-KIF5A/NKHC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-KIF5A/NKHC1 Polyclonal Antibody

Anti-KIF5A/NKHC1 Polyclonal Antibody

😃Good
Catalog No. TMAB-08050
Anti-KIF5A/NKHC1 Polyclonal Antibody is a Rabbit antibody targeting KIF5A/NKHC1. Anti-KIF5A/NKHC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-KIF5A/NKHC1 Polyclonal Antibody is a Rabbit antibody targeting KIF5A/NKHC1. Anti-KIF5A/NKHC1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Note=Concentrated in the cell body of the neurons, particularly in the perinuclear region.
Tissue SpecificityDistributed throughout the CNS but is highly enriched in subsets of neurons.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNKHC1 is a neuronal-specific component of a multi-subunit “molecular motor” complex that mediates intracellular organelle transport. Mutations in the gene encoding NKHC1 cause autosomal dominant spastic paraplegia 10. NKHC1 has a pan-neuronal distribution in the nervous system. Rat tissue extracts by immunoblot of NKHC1 can produce a doublet only in brain and sciatic nerve tissue. NKHC1 is distributed throughout the central nervous system and is enriched in subsets of neurons. Within cultured hippocampal neurons, NKHC1 is concentrated in the perinuclear region of the cell body. Kinesin superfamily proteins like NKHC1 are the molecular motors conveying cargos along microtubules.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human KIF5A/NKHC1
Antigen Species
Human
Gene Name
KIF5A
Gene ID
3798
Protein Name
Kinesin heavy chain isoform 5A
Uniprot ID
Q12840
Function
Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL).
Chemical Properties
Molecular WeightTheoretical: 113 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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