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Anti-AMHR2 Polyclonal Antibody 2

Catalog No. TMAB-02515 Copy Product Info
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Anti-AMHR2 Polyclonal Antibody 2 is a Rabbit antibody targeting AMHR2. Anti-AMHR2 Polyclonal Antibody 2 can be used in WB.

Anti-AMHR2 Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAB-02515

Anti-AMHR2 Polyclonal Antibody 2 is a Rabbit antibody targeting AMHR2. Anti-AMHR2 Polyclonal Antibody 2 can be used in WB.

Anti-AMHR2 Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-AMHR2 Polyclonal Antibody 2 is a Rabbit antibody targeting AMHR2. Anti-AMHR2 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Pig,Horse)
Verified Activity
1. Sample:
Jurkat (Human) Cell Lysate at 30 μg
Primary: Anti-AMHR2 (TMAB-02515) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kD
Observed band size: 63 kD
2. Sample:
293T Cell (Human) Lysate at 30 μg
Primary: Anti-AMHR2 (TMAB-02515) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kD
Observed band size: 61 kD
3. Sample:
Lane 1: Mouse Adrenal gland tissue lysates
Lane 2: Rat Adrenal gland tissue lysates
Primary: Anti-AMHR2 (TMAB-02515) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kDa
Observed band size: 61 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors phospho-rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MISRII/AMHR2
Antigen Species
Human
Gene Name
AMHR2
Gene ID
Protein Name
Muellerian hormone type-2 receptor
Uniprot ID
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Chemical Properties
Molecular WeightTheoretical: 61 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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