Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody
😃Good
Catalog No. TMAB-10588
Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DDX58 (Thr170). Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody
Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody
😃Good
Catalog No. TMAB-10588
Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DDX58 (Thr170). Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Resource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DDX58 (Thr170). Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Note=Colocalized with TRIM25 at cytoplasmic perinuclear bodies. |
| Tissue Specificity | Present in vascular smooth cells (at protein level). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG1/DDX58) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG1/DDX58 activates the kinases TBK1 and IKKe through the adaptor protein IPS1. These kinases then phosphorylate the transcription factors IRF3 and IRF7 which are essential for the expression of type-I interferons. RIG1/DDX58 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human DDX58 around the phosphorylation site of Thr170 |
| Antigen Species | Human |
| Gene Name | DDX58 |
| Gene ID | |
| Protein Name | Antiviral innate immune response receptor RIG-I |
| Uniprot ID | |
| Function | Involved in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). Essential for the production of interferons in response to RNA viruses including paramyxoviruses, influenza viruses, Japanese encephalitis virus and HCV. |
| Molecular Weight | Theoretical: 106 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody | purchase Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody | Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody cost | order Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody | Anti-Phospho-DDX58 (Thr170) Polyclonal Antibody molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.