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Anti-Oligophrenin 1 Polyclonal Antibody 2

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Catalog No. TMAB-09770

Anti-Oligophrenin 1 Polyclonal Antibody 2 is a Rabbit antibody targeting Oligophrenin 1. Anti-Oligophrenin 1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.

Anti-Oligophrenin 1 Polyclonal Antibody 2

Anti-Oligophrenin 1 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-09770
Anti-Oligophrenin 1 Polyclonal Antibody 2 is a Rabbit antibody targeting Oligophrenin 1. Anti-Oligophrenin 1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Oligophrenin 1 Polyclonal Antibody 2 is a Rabbit antibody targeting Oligophrenin 1. Anti-Oligophrenin 1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Horse,Sheep)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction, synapse. Cell projection, axon. Cell projection, dendritic spine. Note=Present in both presynaptic and postsynaptic sites
Tissue SpecificityExpressed in brain.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPreservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
Concentration1mg/ml
Research BackgroundRas p21 can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (1,2). Interaction of Ras p21 with GTPase activating protein (GAP) can increase the rate of hydrolysis of Ras p21-bound GTP by as much as 1000-fold (3). In mitogenically activated and tyrosine kinase-transformed cells, Ras GAP forms a complex with a protein designated p190 (4). At its amino terminus, p190 contains sequence motifs characteristic of all known GTPases, whereas the carboxy terminus contains sequences similar to those found in the Bcr gene product, n-chimerin and Rho GAP, all of which exhibit intrinsic GAP activity (4,5). Oligophrenein-1 is an additional protein with GTPase activating activity. Oligophrenein-1 is a RhoGAP protein that stimulates GTP hydrolysis of Rho subfamily members and is involved in cell migration, morphogenesis and axon outgrowth (6).
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Oligophrenin 1
Antigen Species
Human
Gene Name
OPHN1
Gene ID
Protein Name
Oligophrenin-1
Uniprot ID
Function
Stimulates GTP hydrolysis of members of the Rho family. Could activates GTPase targets that are known to affect cell migration and outgrowth of axons and dendrites.
Chemical Properties
Molecular WeightTheoretical: 92 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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