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Anti-LRRTM3 Polyclonal Antibody
Catalog No. TMAB-08427 Copy Product Info
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Anti-LRRTM3 Polyclonal Antibody is a Rabbit antibody targeting LRRTM3. Anti-LRRTM3 Polyclonal Antibody can be used in FCM.
Anti-LRRTM3 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-08427
Anti-LRRTM3 Polyclonal Antibody is a Rabbit antibody targeting LRRTM3. Anti-LRRTM3 Polyclonal Antibody can be used in FCM.
Anti-LRRTM3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
Antigen Details
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| Description | Anti-LRRTM3 Polyclonal Antibody is a Rabbit antibody targeting LRRTM3. Anti-LRRTM3 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Rabbit,Sheep,Monkey) |
| Verified Activity | Blank control (blue line): Mouse brain (fixed with 2% paraformaldehyde for 10 min at room temperature, and then stained with Primary Antibody for 30 min at room temperature). Primary Antibody (green line): Rabbit Anti-LRRTM3 antibody (TMAB-08427), Dilution: 1 μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG. Secondary Antibody (white blue line): Goat anti-rabbit IgG-FITC, Dilution: 1 μg /test. |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein |
| Tissue Specificity | Expressed in neuronal tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM3 (leucine rich repeat transmembrane neuronal 3) is a 581 amino acid single-pass type I membrane protein belonging to the LRRTM family. LRRTM3 is involved in the development and maintenance of the vertebrate nervous system, and contains ten LRR repeats. Expressed in neuronal tissues, LRRTM3 is encoded by a gene that maps to a region of chromosome 10 that has been linked to late-onset Alzheimer disease and elevated plasma Beta-Amyloid. As a result of alternative splicing events, two LRRTM3 isoforms exist. |
| Immunogen | KLH conjugated synthetic peptide: human LRRTM3 |
| Antigen Species | Human |
| Gene Name | LRRTM3 |
| Gene ID | |
| Protein Name | Leucine-rich repeat transmembrane neuronal protein 3 |
| Uniprot ID | |
| Function | May play a role in the development and maintenance of the vertebrate nervous system. |
| Molecular Weight | Theoretical: 63 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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