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Anti-HMGCL Polyclonal Antibody
😃Good
Catalog No. TMAB-07186
Anti-HMGCL Polyclonal Antibody is a Rabbit antibody targeting HMGCL. Anti-HMGCL Polyclonal Antibody can be used in WB.
Anti-HMGCL Polyclonal Antibody
Anti-HMGCL Polyclonal Antibody
😃Good
Catalog No. TMAB-07186
Anti-HMGCL Polyclonal Antibody is a Rabbit antibody targeting HMGCL. Anti-HMGCL Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HMGCL Polyclonal Antibody is a Rabbit antibody targeting HMGCL. Anti-HMGCL Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion matrix. |
| Tissue Specificity | Fibroblasts, liver and lymphoblasts. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Hydroxymethylglutaryl-CoA lyase (HMGCL) is found in fibroblasts, liver and lymphoblasts. It has a role in ketogenesis and leucine catabolism. Defects in HMGCL are the cause of 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (hydroxymethylglutaricaciduria), an autosomal recessive disease which can lead to hypoglycemia and coma. |
| Immunogen | KLH conjugated synthetic peptide: human HMGCL |
| Antigen Species | Human |
| Gene Name | HMGCL |
| Gene ID | |
| Protein Name | Hydroxymethylglutaryl-CoA lyase, mitochondrial |
| Uniprot ID | |
| Function | Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. |
| Molecular Weight | Theoretical: 32 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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