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Anti-SLC19A3 Polyclonal Antibody
😃Good
Catalog No. TMAB-12846
Anti-SLC19A3 Polyclonal Antibody is a Rabbit antibody targeting SLC19A3. Anti-SLC19A3 Polyclonal Antibody can be used in WB.
Anti-SLC19A3 Polyclonal Antibody
Anti-SLC19A3 Polyclonal Antibody
😃Good
Catalog No. TMAB-12846
Anti-SLC19A3 Polyclonal Antibody is a Rabbit antibody targeting SLC19A3. Anti-SLC19A3 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SLC19A3 Polyclonal Antibody is a Rabbit antibody targeting SLC19A3. Anti-SLC19A3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Plasma membrane. |
| Tissue Specificity | Widely expressed but most abundant in placenta, kidney and liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity. Mutations in this gene cause biotin-responsive basal ganglia disease (BBGD); a recessive disorder manifested in childhood that progresses to chronic encephalopathy, dystonia, quadriparesis, and death if untreated. Patients with BBGD have bilateral necrosis in the head of the caudate nucleus and in the putamen. Administration of high doses of biotin in the early progression of the disorder eliminates pathological symptoms while delayed treatment results in residual paraparesis, mild mental retardation, or dystonia. Administration of thiamine is ineffective in the treatment of this disorder. Experiments have failed to show that this protein can transport biotin. Mutations in this gene also cause a Wernicke's-like encephalopathy.[provided by RefSeq, Jan 2010] |
| Immunogen | KLH conjugated synthetic peptide: human SLC19A3 |
| Antigen Species | Human |
| Gene Name | SLC19A3 |
| Gene ID | |
| Protein Name | Thiamine transporter 2 |
| Uniprot ID | |
| Function | Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity. |
| Molecular Weight | Theoretical: 56 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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