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Anti-BMAL1 Polyclonal Antibody 2
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Catalog No. TMAB-03158
Anti-BMAL1 Polyclonal Antibody 2 is a Rabbit antibody targeting BMAL1. Anti-BMAL1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Anti-BMAL1 Polyclonal Antibody 2
Anti-BMAL1 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-03158
Anti-BMAL1 Polyclonal Antibody 2 is a Rabbit antibody targeting BMAL1. Anti-BMAL1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-BMAL1 Polyclonal Antibody 2 is a Rabbit antibody targeting BMAL1. Anti-BMAL1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Chicken,Pig,Cow,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Highly expressed in the adult brain, skeletal muscle and heart. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection, including COVID-19. [provided by RefSeq, Oct 2021] |
| Immunogen | KLH conjugated synthetic peptide: human BMAL1 |
| Antigen Species | Human |
| Gene Name | BMAL1 |
| Gene ID | |
| Protein Name | Basic helix-loop-helix ARNT-like protein 1 |
| Uniprot ID | |
| Function | ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins. |
| Molecular Weight | Theoretical: 69 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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