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Anti-Netrin G2 Polyclonal Antibody

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Catalog No. TMAB-09369

Anti-Netrin G2 Polyclonal Antibody is a Rabbit antibody targeting Netrin G2. Anti-Netrin G2 Polyclonal Antibody can be used in WB.

Anti-Netrin G2 Polyclonal Antibody

Anti-Netrin G2 Polyclonal Antibody

😃Good
Catalog No. TMAB-09369
Anti-Netrin G2 Polyclonal Antibody is a Rabbit antibody targeting Netrin G2. Anti-Netrin G2 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Netrin G2 Polyclonal Antibody is a Rabbit antibody targeting Netrin G2. Anti-Netrin G2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Cow,Sheep)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNetrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin-1, which is the mammalian homolog of UNC-6 from C. elegans, is largely expressed in the developing nervous system and in mesodermal tissues. Netrin-1 is expressed by the floor plate as either a cell associated protein or in a diffusible form, and it binds to several surface receptor components, including deleted in colorectal cancer (DCC) and neogenin. During embryonic development, netrin-1 diffuses through the neuronal epithelium, where it forms a chemoattractant gradient that directs axonal migration to the ventral midline of the spinal cord. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins, as the cells are repelled, rather than attracted, by the netrin gradient.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Netrin G2
Antigen Species
Human
Gene Name
NTNG2
Gene ID
Protein Name
Netrin-G2
Uniprot ID
Function
Promotes neurite outgrowth of both axons and dendrites.
Chemical Properties
Molecular WeightTheoretical: 56 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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