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Anti-NHEDC2 Polyclonal Antibody
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Catalog No. TMAB-09465
Anti-NHEDC2 Polyclonal Antibody is a Rabbit antibody targeting NHEDC2. Anti-NHEDC2 Polyclonal Antibody can be used in WB.
Anti-NHEDC2 Polyclonal Antibody
Anti-NHEDC2 Polyclonal Antibody
😃Good
Catalog No. TMAB-09465
Anti-NHEDC2 Polyclonal Antibody is a Rabbit antibody targeting NHEDC2. Anti-NHEDC2 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Antigen Details
Chemical Properties
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| Description | Anti-NHEDC2 Polyclonal Antibody is a Rabbit antibody targeting NHEDC2. Anti-NHEDC2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion membrane; Multi-pass membraneprotein (By similarity). |
| Tissue Specificity | Detected in red blood cells (at proteinlevel). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human NHEDC2 |
| Antigen Species | Human |
| Gene Name | SLC9B2 |
| Gene ID | |
| Protein Name | Sodium/hydrogen exchanger 9B2 |
| Uniprot ID | |
| Function | Electroneutral exchange of protons for Na(+) and Li(+)across the inner mitochondrial membrane. Contributes to theorganellar volume homeostasis. Required for osteoclastdifferentiation and bone resorption activity (By similarity). |
| Molecular Weight | Theoretical: 58 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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