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Anti-NHEDC2 Polyclonal Antibody

Catalog No. TMAB-09465 Copy Product Info
🥰Excellent
Anti-NHEDC2 Polyclonal Antibody is a Rabbit antibody targeting NHEDC2. Anti-NHEDC2 Polyclonal Antibody can be used in WB.

Anti-NHEDC2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09465

Anti-NHEDC2 Polyclonal Antibody is a Rabbit antibody targeting NHEDC2. Anti-NHEDC2 Polyclonal Antibody can be used in WB.

Anti-NHEDC2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NHEDC2 Polyclonal Antibody is a Rabbit antibody targeting NHEDC2. Anti-NHEDC2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Dog,Rabbit)
Verified Activity
1. Sample: Spinal cord (Mouse) Lysate at 40 μg Kidney (Mouse) Lysate at 40 μg Primary: Anti-NHEDC2 (TMAB-09465) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 53 kD
2. Sample:
Lane 1: HL60 (Human) Cell Lysate at 30 μg
Lane 2: Hcclm3 (Human) Cell Lysate at 30 μg
Lane 3: Molt-4 (Human) Cell Lysate at 30 μg
Lane 4: U937 (Human) Cell Lysate at 30 μg
Primary: Anti-NHEDC2 (TMAB-09465) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kD
Observed band size: 50 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion membrane; Multi-pass membraneprotein (By similarity).
Tissue SpecificityDetected in red blood cells (at proteinlevel).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNa+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NHEDC2
Antigen Species
Human
Gene Name
SLC9B2
Gene ID
133308
Protein Name
Sodium/hydrogen exchanger 9B2
Uniprot ID
Q86UD5
Function
Electroneutral exchange of protons for Na(+) and Li(+)across the inner mitochondrial membrane. Contributes to theorganellar volume homeostasis. Required for osteoclastdifferentiation and bone resorption activity (By similarity).
Chemical Properties
Molecular WeightTheoretical: 58 kDa. Actual: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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