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Anti-TRMT1 Polyclonal Antibody
Catalog No. TMAB-13823 Copy Product Info
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Anti-TRMT1 Polyclonal Antibody is a Rabbit antibody targeting TRMT1. Anti-TRMT1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-TRMT1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-13823
Anti-TRMT1 Polyclonal Antibody is a Rabbit antibody targeting TRMT1. Anti-TRMT1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-TRMT1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TRMT1 Polyclonal Antibody is a Rabbit antibody targeting TRMT1. Anti-TRMT1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Pig,Cow,Sheep) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (TRMT1) Polyclonal Antibody, Unconjugated (TMAB-13823) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Transfer RNA (tRNA) modifications help regulate the efficiency of mRNA translation by maintaining the correct reading frames. N(2),N(2)-dimethylguanosine tRNA methyltransferase, also known as TRMT1 or tRNA(guanine-26,N(2)-N(2)) methyltransferase, is a 659 amino acid enzyme that is responsible for tRNA modifications in eukaryotes. Using S-adenosyl-L-methionine as a methyl donor, TRMT1 dimethylates a single guanine residue at position 26 of tRNA. TRMT1, which was initially identified in yeast and C. elegans, has a 26% and 31% sequence identity to its yeast and C. elegans homologs, respectively. There are two isoforms of TRMT1 produced by alternative splicing events. The TRMT1 gene maps to chromosome 19p13.13 and mutations in this gene lead to abrogated enzyme activity and a decrease in protein levels. |
| Immunogen | KLH conjugated synthetic peptide: human TRMT1 |
| Antigen Species | Human |
| Gene Name | TRMT1 |
| Gene ID | |
| Protein Name | tRNA(guanine(26)-N(2))-dimethyltransferase |
| Uniprot ID | |
| Function | Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. |
| Molecular Weight | Theoretical: 72 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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