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Anti-PHEX Polyclonal Antibody

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Catalog No. TMAB-10265

Anti-PHEX Polyclonal Antibody is a Rabbit antibody targeting PHEX. Anti-PHEX Polyclonal Antibody can be used in FCM.

Anti-PHEX Polyclonal Antibody

Anti-PHEX Polyclonal Antibody

😃Good
Catalog No. TMAB-10265
Anti-PHEX Polyclonal Antibody is a Rabbit antibody targeting PHEX. Anti-PHEX Polyclonal Antibody can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PHEX Polyclonal Antibody is a Rabbit antibody targeting PHEX. Anti-PHEX Polyclonal Antibody can be used in FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Application
FCM
Recommended Dose
FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
Tissue SpecificityLymphocytes and fetal brain; not in adult brain, placenta, skeletal muscle and pancreas; not in adult and fetal heart, lung, liver and kidney.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: Human PHEX
Antigen Species
Human
Gene Name
PHEX
Gene ID
5251
Protein Name
Phosphate-regulating neutral endopeptidase PHEX
Uniprot ID
P78562
Function
Probably involved in bone and dentin mineralization and renal phosphate reabsorption.
Chemical Properties
Molecular WeightTheoretical: 86 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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