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Anti-FAM3C Polyclonal Antibody

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Catalog No. TMAB-05864

Anti-FAM3C Polyclonal Antibody is a Rabbit antibody targeting FAM3C. Anti-FAM3C Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-FAM3C Polyclonal Antibody

Anti-FAM3C Polyclonal Antibody

😃Good
Catalog No. TMAB-05864
Anti-FAM3C Polyclonal Antibody is a Rabbit antibody targeting FAM3C. Anti-FAM3C Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FAM3C Polyclonal Antibody is a Rabbit antibody targeting FAM3C. Anti-FAM3C Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted. Cytoplasmic vesicle. Note=Cytoplasmic in some cancer cells.
Tissue SpecificityPresent in most secretory epithelia (at protein level).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF∫-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FAM3C
Antigen Species
Human
Gene Name
FAM3C
Gene ID
Protein Name
Protein FAM3C
Uniprot ID
Function
May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition.
Chemical Properties
Molecular WeightTheoretical: 22 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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