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Anti-DNA polymerase mu Polyclonal Antibody
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Catalog No. TMAB-05221
Anti-DNA polymerase mu Polyclonal Antibody is a Rabbit antibody targeting DNA polymerase mu. Anti-DNA polymerase mu Polyclonal Antibody can be used in WB.
Anti-DNA polymerase mu Polyclonal Antibody
Anti-DNA polymerase mu Polyclonal Antibody
😃Good
Catalog No. TMAB-05221
Anti-DNA polymerase mu Polyclonal Antibody is a Rabbit antibody targeting DNA polymerase mu. Anti-DNA polymerase mu Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DNA polymerase mu Polyclonal Antibody is a Rabbit antibody targeting DNA polymerase mu. Anti-DNA polymerase mu Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in a number of tissues. Abundant in thymus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair. |
| Immunogen | KLH conjugated synthetic peptide: human DNA polymerase mu |
| Antigen Species | Human |
| Gene Name | POLM |
| Gene ID | |
| Protein Name | DNA-directed DNA/RNA polymerase mu |
| Uniprot ID | |
| Function | Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. |
| Molecular Weight | Theoretical: 55 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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