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Anti-DNA polymerase mu Polyclonal Antibody
Catalog No. TMAB-05221 Copy Product Info
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Anti-DNA polymerase mu Polyclonal Antibody is a Rabbit antibody targeting DNA polymerase mu. Anti-DNA polymerase mu Polyclonal Antibody can be used in WB.
Anti-DNA polymerase mu Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-05221
Anti-DNA polymerase mu Polyclonal Antibody is a Rabbit antibody targeting DNA polymerase mu. Anti-DNA polymerase mu Polyclonal Antibody can be used in WB.
Anti-DNA polymerase mu Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-DNA polymerase mu Polyclonal Antibody is a Rabbit antibody targeting DNA polymerase mu. Anti-DNA polymerase mu Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Horse) |
| Verified Activity | 1. Sample: HepG2 Cell (Human) Lysate at 30 μg Primary: Anti-DNA polymerase mu (TMAB-05221) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 60 kD 2. Sample: Raji Cell (Human) Lysate at 30 μg Primary: Anti-DNA polymerase mu (TMAB-05221) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 60 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in a number of tissues. Abundant in thymus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair. |
| Immunogen | KLH conjugated synthetic peptide: human DNA polymerase mu |
| Antigen Species | Human |
| Gene Name | POLM |
| Gene ID | |
| Protein Name | DNA-directed DNA/RNA polymerase mu |
| Uniprot ID | |
| Function | Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. |
| Molecular Weight | Theoretical: 55 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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