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Anti-POFUT2 Polyclonal Antibody

Catalog No. TMAB-11614 Copy Product Info
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Anti-POFUT2 Polyclonal Antibody is a Rabbit antibody targeting POFUT2. Anti-POFUT2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-POFUT2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-11614

Anti-POFUT2 Polyclonal Antibody is a Rabbit antibody targeting POFUT2. Anti-POFUT2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-POFUT2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-POFUT2 Polyclonal Antibody is a Rabbit antibody targeting POFUT2. Anti-POFUT2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (POFUT2) Polyclonal Antibody, Unconjugated (TMAB-11614) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum.
Tissue SpecificityIsoform A is expressed in fetal liver and peripheral blood lymphocytes. Isoform B is expressed in spleen, lung, testis, bone marrow, thymus, pancreas, prostate, fetal brain, fetal liver and fetal kidney. Isoform C is expressed in brain, heart, spleen, liver, lung, stomach, testis, placenta, skin, thymus, pancreas, mammary gland, prostate, fetal brain, fetal liver and fetal heart.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundFucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human POFUT2
Antigen Species
Human
Gene Name
POFUT2
Gene ID
23275
Protein Name
GDP-fucose protein O-fucosyltransferase 2
Uniprot ID
Q9Y2G5
Function
Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats.
Chemical Properties
Molecular WeightTheoretical: 25, 50 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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