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Anti-MARVELD1 Polyclonal Antibody
😃Good
Catalog No. TMAB-08619
Anti-MARVELD1 Polyclonal Antibody is a Rabbit antibody targeting MARVELD1. Anti-MARVELD1 Polyclonal Antibody can be used in WB.
Anti-MARVELD1 Polyclonal Antibody
Anti-MARVELD1 Polyclonal Antibody
😃Good
Catalog No. TMAB-08619
Anti-MARVELD1 Polyclonal Antibody is a Rabbit antibody targeting MARVELD1. Anti-MARVELD1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MARVELD1 Polyclonal Antibody is a Rabbit antibody targeting MARVELD1. Anti-MARVELD1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Nucleus. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization. |
| Tissue Specificity | Widely expressed in normal tissues. Down-regulated in multiple primary tumors. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity. |
| Immunogen | KLH conjugated synthetic peptide: human MARVELD1 |
| Antigen Species | Human |
| Gene Name | MARVELD1 |
| Gene ID | |
| Protein Name | MARVEL domain-containing protein 1 |
| Uniprot ID | |
| Function | Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration |
| Molecular Weight | Theoretical: 19 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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