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Anti-PCDHA10/CNRN8 Polyclonal Antibody
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Catalog No. TMAB-10054
Anti-PCDHA10/CNRN8 Polyclonal Antibody is a Rabbit antibody targeting PCDHA10/CNRN8. Anti-PCDHA10/CNRN8 Polyclonal Antibody can be used in WB.
Anti-PCDHA10/CNRN8 Polyclonal Antibody
Anti-PCDHA10/CNRN8 Polyclonal Antibody
😃Good
Catalog No. TMAB-10054
Anti-PCDHA10/CNRN8 Polyclonal Antibody is a Rabbit antibody targeting PCDHA10/CNRN8. Anti-PCDHA10/CNRN8 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PCDHA10/CNRN8 Polyclonal Antibody is a Rabbit antibody targeting PCDHA10/CNRN8. Anti-PCDHA10/CNRN8 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. These genes generate thousands of different protocadherin proteins through alternative promoter usage and cis-alternative splicing. PCDHA and PCDHG family members form oligomers, which also increases the diversity of PCDH proteins at the cell surface. All three gene clusters, PCDHA, PCDHB, and PCDHG show upregulated expression during brain development, and PCDHA is subsequently downregulated by myelination. Expression of all three clusters continues in the olfactory bulb, hippocampus and cerebellum until adulthood. Members of the PCDH family are potential targets in schizophrenia and bipolar disorder pathogenesis. PCDHA10 produces at least three isoforms by alternative splicing. |
| Immunogen | KLH conjugated synthetic peptide: human PCDHA10/CNRN8 |
| Antigen Species | Human |
| Gene Name | PCDHA10 |
| Gene ID | |
| Protein Name | Protocadherin alpha-10 |
| Uniprot ID | |
| Function | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
| Molecular Weight | Theoretical: 100 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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