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Anti-Phospho-PLCG 2 (Tyr759) Polyclonal Antibody

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Catalog No. TMAB-11170 Copy Product Info
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Anti-Phospho-PLCG 2 (Tyr759) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCG 2 (Tyr759). Anti-Phospho-PLCG 2 (Tyr759) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-PLCG 2
(Tyr759) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-PLCG 2 (Tyr759) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCG 2 (Tyr759). Anti-Phospho-PLCG 2 (Tyr759) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundEnzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide specific phospholipase C enzymes, C beta is regulated by heterotrimeric G protein coupled receptors, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases. The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human PLC gamma 2 around the phosphorylation site of Tyr759
Antigen Species
Human
Gene Name
PLCG2
Gene ID
Protein Name
1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-2
Uniprot ID
Function
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Chemical Properties
Molecular WeightTheoretical: 147 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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