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Anti-Topoisomerase III Polyclonal Antibody
Catalog No. TMAB-13679 Copy Product Info
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Anti-Topoisomerase III Polyclonal Antibody is a Rabbit antibody targeting Topoisomerase III. Anti-Topoisomerase III Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Topoisomerase III Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-13679
Anti-Topoisomerase III Polyclonal Antibody is a Rabbit antibody targeting Topoisomerase III. Anti-Topoisomerase III Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Topoisomerase III Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Topoisomerase III Polyclonal Antibody is a Rabbit antibody targeting Topoisomerase III. Anti-Topoisomerase III Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse) |
| Verified Activity | Tissue/cell: Rat testis tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-TOP3 Polyclonal Antibody, Unconjugated (TMAB-13679) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | High expression is found in testis, heart, skeletal muscle and pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human Topoisomerase III |
| Antigen Species | Human |
| Gene Name | TOP3A |
| Gene ID | |
| Protein Name | DNA topoisomerase 3-alpha |
| Uniprot ID | |
| Function | Reduces the number of supercoils in a highly negatively supercoiled DNA. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. |
| Molecular Weight | Theoretical: 112 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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