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Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody

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Catalog No. TMAB-10571

Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DAAM1 (Thr361). Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody can be used in WB.

Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody

Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody

😃Good
Catalog No. TMAB-10571
Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DAAM1 (Thr361). Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DAAM1 (Thr361). Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit,Sheep,GuineaPig)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Note=Perinuclear.
Tissue SpecificityExpressed in all tissues examined.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDAAM1 (Dishevelled associated activator of morphogenesis 1) is a diaphanous-related formin which binds to dishevelled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex assembly. It is an essential component of noncanonical Wnt signaling. DAAM1 also communicates with Rho GTPases, CIP4 and Src in the regulation of the signalling pathways that co-ordinate the dynamics of the actin filament system. DAAM1 may be a coordinator of endocytosis and cytoskeletal remodeling.
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human DAAM1 around the phosphorylation site of Thr361
Antigen Species
Human
Gene Name
DAAM1
Gene ID
23002
Protein Name
Disheveled-associated activator of morphogenesis 1
Uniprot ID
Q9Y4D1
Function
Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments.
Chemical Properties
Molecular WeightTheoretical: 120-130 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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