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Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody
Catalog No. TMAB-10571 Copy Product Info
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Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DAAM1 (Thr361). Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody can be used in WB.
Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-10571
Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DAAM1 (Thr361). Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody can be used in WB.
Anti-Phospho-DAAM1
(Thr361) Polyclonal Antibody
(Thr361) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DAAM1 (Thr361). Anti-Phospho-DAAM1 (Thr361) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit,Sheep,GuineaPig) |
| Verified Activity | Sample: A431 (Human) Cell Lysate at 30 μg Primary: Anti-phospho-DAAM1 (Thr361) (TMAB-10571) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 120-130 kD Observed band size: 125 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Note=Perinuclear. |
| Tissue Specificity | Expressed in all tissues examined. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | DAAM1 (Dishevelled associated activator of morphogenesis 1) is a diaphanous-related formin which binds to dishevelled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex assembly. It is an essential component of noncanonical Wnt signaling. DAAM1 also communicates with Rho GTPases, CIP4 and Src in the regulation of the signalling pathways that co-ordinate the dynamics of the actin filament system. DAAM1 may be a coordinator of endocytosis and cytoskeletal remodeling. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human DAAM1 around the phosphorylation site of Thr361 |
| Antigen Species | Human |
| Gene Name | DAAM1 |
| Gene ID | |
| Protein Name | Disheveled-associated activator of morphogenesis 1 |
| Uniprot ID | |
| Function | Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. |
| Molecular Weight | Theoretical: 120-130 kDa. Actual: 125 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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