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Anti-MORG1 Polyclonal Antibody

Catalog No. TMAB-08944 Copy Product Info
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Anti-MORG1 Polyclonal Antibody is a Rabbit antibody targeting MORG1. Anti-MORG1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-MORG1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-08944

Anti-MORG1 Polyclonal Antibody is a Rabbit antibody targeting MORG1. Anti-MORG1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-MORG1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MORG1 Polyclonal Antibody is a Rabbit antibody targeting MORG1. Anti-MORG1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MORG1) Polyclonal Antibody, Unconjugated (TMAB-08944) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Predominantly cytoplasmic (By similarity). Partially nuclear.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MORG1
Antigen Species
Human
Gene Name
WDR83
Gene ID
Protein Name
WD repeat domain-containing protein 83
Uniprot ID
Function
Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.
Chemical Properties
Molecular WeightTheoretical: 34 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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