Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-Phospho-Separase (Ser1073) Polyclonal Antibody
😃Good
Catalog No. TMAB-11270
Anti-Phospho-Separase (Ser1073) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Separase (Ser1073). Anti-Phospho-Separase (Ser1073) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-Separase (Ser1073) Polyclonal Antibody
Anti-Phospho-Separase (Ser1073) Polyclonal Antibody
😃Good
Catalog No. TMAB-11270
Anti-Phospho-Separase (Ser1073) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Separase (Ser1073). Anti-Phospho-Separase (Ser1073) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Resource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Separase (Ser1073) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Separase (Ser1073). Anti-Phospho-Separase (Ser1073) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic and Nuclear |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids. Each cell must receive one chromatid of every chromosome, during mitosis. Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys cohesin by means of cleavage, allowing the chromatids to separate and divide with the cell. Separase activity is highly regulated. It not only cleaves cohesin at the onset of anaphase but also cleaves itself, promoting downregulation of separase after anaphase. Should a human cell become an aneuploid (one too many or too few chromatids), the embryo most likely will not survive. Should the embryo survive, it will most likely develop severe birth defects or later develop malignant cancers. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human ESPL1 around the phosphorylation site of Ser1073 |
| Antigen Species | Human |
| Gene Name | ESPL1 |
| Gene ID | |
| Protein Name | Separin |
| Uniprot ID | |
| Function | Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. |
| Molecular Weight | Theoretical: 198 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Phospho-Separase (Ser1073) Polyclonal Antibody | purchase Anti-Phospho-Separase (Ser1073) Polyclonal Antibody | Anti-Phospho-Separase (Ser1073) Polyclonal Antibody cost | order Anti-Phospho-Separase (Ser1073) Polyclonal Antibody | Anti-Phospho-Separase (Ser1073) Polyclonal Antibody molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.