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Anti-RSPO3 Polyclonal Antibody
Catalog No. TMAB-12407 Copy Product Info
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Anti-RSPO3 Polyclonal Antibody is a Rabbit antibody targeting RSPO3. Anti-RSPO3 Polyclonal Antibody can be used in WB.
Anti-RSPO3 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-12407
Anti-RSPO3 Polyclonal Antibody is a Rabbit antibody targeting RSPO3. Anti-RSPO3 Polyclonal Antibody can be used in WB.
Anti-RSPO3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-RSPO3 Polyclonal Antibody is a Rabbit antibody targeting RSPO3. Anti-RSPO3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,GuineaPig,Cat) |
| Verified Activity | Sample: Lane 1: Human Hela cell lysates Lane 2: Human Lovo cell lysates Lane 3: Human A549 cell lysates Lane 4: Human Huvec cell lysates Primary: Anti-RSPO3 (TMAB-12407) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 31 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Ubiquitously expressed. Expressed at higher level in placenta, small intestine, fetal thymus and lymph node. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013] |
| Immunogen | KLH conjugated synthetic peptide: human RSPO3 |
| Antigen Species | Human |
| Gene Name | RSPO3 |
| Gene ID | |
| Protein Name | R-spondin-3 |
| Uniprot ID | |
| Function | Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. |
| Molecular Weight | Theoretical: 31 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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