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Anti-Neurotensin Receptor 2 Polyclonal Antibody
Catalog No. TMAB-09410 Copy Product Info
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Anti-Neurotensin Receptor 2 Polyclonal Antibody is a Rabbit antibody targeting Neurotensin Receptor 2. Anti-Neurotensin Receptor 2 Polyclonal Antibody can be used in WB.
Anti-Neurotensin Receptor 2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-09410
Anti-Neurotensin Receptor 2 Polyclonal Antibody is a Rabbit antibody targeting Neurotensin Receptor 2. Anti-Neurotensin Receptor 2 Polyclonal Antibody can be used in WB.
Anti-Neurotensin Receptor 2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-Neurotensin Receptor 2 Polyclonal Antibody is a Rabbit antibody targeting Neurotensin Receptor 2. Anti-Neurotensin Receptor 2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Cow,Rabbit,Sheep) |
| Verified Activity | Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Human U87MG cell lysates Primary: Anti-Neurotensin Receptor 2 (TMAB-09410) at 1/200 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kDa Observed band size: 43 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner. |
| Immunogen | KLH conjugated synthetic peptide: human Neurotensin Receptor 2 |
| Antigen Species | Human |
| Gene Name | NTSR2 |
| Gene ID | |
| Protein Name | Neurotensin receptor type 2 |
| Uniprot ID | |
| Function | Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Molecular Weight | Theoretical: 45 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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