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Anti-Neurotensin Receptor 2 Polyclonal Antibody

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Catalog No. TMAB-09410

Anti-Neurotensin Receptor 2 Polyclonal Antibody is a Rabbit antibody targeting Neurotensin Receptor 2. Anti-Neurotensin Receptor 2 Polyclonal Antibody can be used in WB.

Anti-Neurotensin Receptor 2 Polyclonal Antibody

Anti-Neurotensin Receptor 2 Polyclonal Antibody

😃Good
Catalog No. TMAB-09410
Anti-Neurotensin Receptor 2 Polyclonal Antibody is a Rabbit antibody targeting Neurotensin Receptor 2. Anti-Neurotensin Receptor 2 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Neurotensin Receptor 2 Polyclonal Antibody is a Rabbit antibody targeting Neurotensin Receptor 2. Anti-Neurotensin Receptor 2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Dog,Cow,Rabbit,Sheep)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNeurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Neurotensin Receptor 2
Antigen Species
Human
Gene Name
NTSR2
Gene ID
Protein Name
Neurotensin receptor type 2
Uniprot ID
Function
Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Chemical Properties
Molecular WeightTheoretical: 45 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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