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Anti-CREB3L1 Polyclonal Antibody

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Catalog No. TMAB-04651

Anti-CREB3L1 Polyclonal Antibody is a Rabbit antibody targeting CREB3L1. Anti-CREB3L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CREB3L1 Polyclonal Antibody

Anti-CREB3L1 Polyclonal Antibody

😃Good
Catalog No. TMAB-04651
Anti-CREB3L1 Polyclonal Antibody is a Rabbit antibody targeting CREB3L1. Anti-CREB3L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CREB3L1 Polyclonal Antibody is a Rabbit antibody targeting CREB3L1. Anti-CREB3L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Cow,Horse)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane and Nucleus. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Tissue SpecificityUbiquitously expressed with high levels in pancreas and prostate. Expressed at relatively lower levels in brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements. [provided by RefSeq, Jun 2013]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CREB3L1
Antigen Species
Human
Gene Name
CREB3L1
Gene ID
90993
Protein Name
Cyclic AMP-responsive element-binding protein 3-like protein 1
Uniprot ID
Q96BA8
Function
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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