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Anti-IRF9/ISGF3 Polyclonal Antibody
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Catalog No. TMAB-07807
Anti-IRF9/ISGF3 Polyclonal Antibody is a Rabbit antibody targeting IRF9/ISGF3. Anti-IRF9/ISGF3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-IRF9/ISGF3 Polyclonal Antibody
Anti-IRF9/ISGF3 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-07807
Anti-IRF9/ISGF3 Polyclonal Antibody is a Rabbit antibody targeting IRF9/ISGF3. Anti-IRF9/ISGF3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Antigen Details
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| Description | Anti-IRF9/ISGF3 Polyclonal Antibody is a Rabbit antibody targeting IRF9/ISGF3. Anti-IRF9/ISGF3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-IRF9 Polyclonal Antibody, Unconjugated (TMAB-07807) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. |
| Immunogen | KLH conjugated synthetic peptide: human IRF9/ISGF3 |
| Antigen Species | Human |
| Gene Name | IRF9 |
| Gene ID | |
| Protein Name | Interferon regulatory factor 9 |
| Uniprot ID |
| Molecular Weight | Theoretical: 44 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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