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Anti-NALP4 Polyclonal Antibody 2

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Catalog No. TMAB-09215

Anti-NALP4 Polyclonal Antibody 2 is a Rabbit antibody targeting NALP4. Anti-NALP4 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.

Anti-NALP4 Polyclonal Antibody 2

Anti-NALP4 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-09215
Anti-NALP4 Polyclonal Antibody 2 is a Rabbit antibody targeting NALP4. Anti-NALP4 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-NALP4 Polyclonal Antibody 2 is a Rabbit antibody targeting NALP4. Anti-NALP4 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Pig,Horse)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm and Cytosol
Tissue SpecificityExpressed in the ovaries (at protein level).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). This gene product has a demonstrated role as a negative regulator of autophagy and type I interferon signaling pathways as a result of protein interactions with its NACHT domain. The PYD domain has also been shown to be important in the inhibition of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells). [provided by RefSeq, Dec 2016]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NALP4
Antigen Species
Human
Gene Name
NLRP4
Gene ID
Protein Name
NACHT, LRR and PYD domains-containing protein 4
Uniprot ID
Function
Required for cytoplasmic lattice formation, thereby modulates the distribution of organelles during oocyte maturation and zygote development Required for preimplantation development in female fertilityMay be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors (By similarity).
Chemical Properties
Molecular WeightTheoretical: 113 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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