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Anti-SNX17 Polyclonal Antibody
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Catalog No. TMAB-13010
Anti-SNX17 Polyclonal Antibody is a Rabbit antibody targeting SNX17. Anti-SNX17 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-SNX17 Polyclonal Antibody
Anti-SNX17 Polyclonal Antibody
😃Good
Catalog No. TMAB-13010
Anti-SNX17 Polyclonal Antibody is a Rabbit antibody targeting SNX17. Anti-SNX17 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SNX17 Polyclonal Antibody is a Rabbit antibody targeting SNX17. Anti-SNX17 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm |
| Tissue Specificity | Expressed in granulocyte and 198 other tissues |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012] |
| Immunogen | KLH conjugated synthetic peptide: human SNX17 |
| Antigen Species | Human |
| Gene Name | SNX17 |
| Gene ID | |
| Protein Name | Sorting nexin-17 |
| Function | Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels (PubMed:15121882, PubMed:15769472).Binds to NPxY sequences in the cytoplasmic tails of target cargos (PubMed:21512128).Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits (PubMed:28892079, PubMed:22492727).Also required for maintenance of normal cell surface levels of APP and LRP1 (PubMed:16712798, PubMed:19005208).Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (PubMed:16712798).7 Publications |
| Molecular Weight | Theoretical: 53 kDa. |
| Relative Density. | no data available |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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