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Anti-MTF-1 Polyclonal Antibody
Catalog No. TMAB-09062 Copy Product Info
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Anti-MTF-1 Polyclonal Antibody is a Rabbit antibody targeting MTF-1. Anti-MTF-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-MTF-1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-09062
Anti-MTF-1 Polyclonal Antibody is a Rabbit antibody targeting MTF-1. Anti-MTF-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-MTF-1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MTF-1 Polyclonal Antibody is a Rabbit antibody targeting MTF-1. Anti-MTF-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-MTF-1 Polyclonal Antibody, Unconjugated (TMAB-09062) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein. |
| Immunogen | KLH conjugated synthetic peptide: human MTF-1 |
| Antigen Species | Human |
| Gene Name | MTF1 |
| Gene ID | |
| Protein Name | Metal regulatory transcription factor 1 |
| Uniprot ID | |
| Function | Activates the metallothionein I promoter. Binds to the metal responsive element (MRE). |
| Molecular Weight | Theoretical: 81 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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