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[Ala11,D-Leu15]-Orexin B(human)

Name: [Ala11,D-Leu15]-Orexin B(human)
Brand: TargetMol
SKU: TP1975
Rating: 4.5 (1 reviews)

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Catalog No. TP1975Cas No. 532932-99-3

Alias [Ala11,D-Leu15]-Orexin B

Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.

[Ala11,D-Leu15]-Orexin B(human)

😃Good

Catalog No. TP1975Alias [Ala11,D-Leu15]-Orexin BCas No. 532932-99-3

Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.

Pack Size	Price	Availability	Quantity
1 mg	TBD	35 days

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Product Introduction

Bioactivity

Description	Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.
Targets&IC50	OX1:52 nM (EC50), OX2:0.13 nM (EC50)
Alias	[Ala11,D-Leu15]-Orexin B

Chemical Properties

Molecular Weight	2857.28
Formula	C₁₂₀H₂₀₆N₄₄O₃₅S
Cas No.	532932-99-3
Relative Density.	no data available

Storage & Solubility Information

Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	H2O: 0.3 mg/mL (0.1 mM), Sonication is recommended.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Keywords

[Ala11,D Leu15] Orexin B(human)[Ala11,DLeu15]Orexin B(human)[Ala-11,D-Leu15]-Orexin B(human)

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