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Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody

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Catalog No. TMAB-10635

Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF4EBP1 (Ser111). Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody can be used in WB.

Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody

Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody

😃Good
Catalog No. TMAB-10635
Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF4EBP1 (Ser111). Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF4EBP1 (Ser111). Anti-Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Dog,Cow,Horse)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityLung and testis.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human 4EBP1 around the phosphorylation site of Ser111
Antigen Species
Human
Gene Name
EIF4EBP1
Gene ID
1978
Protein Name
Eukaryotic translation initiation factor 4E-binding protein 1
Uniprot ID
Q13541
Function
Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Chemical Properties
Molecular WeightTheoretical: 13 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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