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Anti-Cytochrome P450 17A1 Polyclonal Antibody
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Catalog No. TMAB-04923
Anti-Cytochrome P450 17A1 Polyclonal Antibody is a Rabbit antibody targeting Cytochrome P450 17A1. Anti-Cytochrome P450 17A1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Cytochrome P450 17A1 Polyclonal Antibody
Anti-Cytochrome P450 17A1 Polyclonal Antibody
😃Good
Catalog No. TMAB-04923
Anti-Cytochrome P450 17A1 Polyclonal Antibody is a Rabbit antibody targeting Cytochrome P450 17A1. Anti-Cytochrome P450 17A1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Cytochrome P450 17A1 Polyclonal Antibody is a Rabbit antibody targeting Cytochrome P450 17A1. Anti-Cytochrome P450 17A1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Cytochrome P450 17A1 (CYP17A1) belongs to the cytochrome P450 family; it plays a role in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. CYP17A1 also catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. CYP17A1 is involved in sexual development during fetal life and at puberty. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5). AH5 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. |
| Immunogen | KLH conjugated synthetic peptide: human P45017A1/Cytochrome P450 17A1 |
| Antigen Species | Human |
| Gene Name | CYP17A1 |
| Gene ID | |
| Protein Name | Steroid 17-alpha-hydroxylase/17, 20 lyase |
| Uniprot ID | |
| Function | Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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