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Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody

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Catalog No. TMAB-11900

Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody is a Rabbit antibody targeting PTGEs/Prostaglandin E Synthase. Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody can be used in WB.

Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody

Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody

😃Good
Catalog No. TMAB-11900
Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody is a Rabbit antibody targeting PTGEs/Prostaglandin E Synthase. Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody is a Rabbit antibody targeting PTGEs/Prostaglandin E Synthase. Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,GuineaPig)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundProstaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PTGEs
Antigen Species
Human
Gene Name
PTGES
Gene ID
9536
Protein Name
Prostaglandin E synthase
Uniprot ID
O14684
Function
Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).
Chemical Properties
Molecular WeightTheoretical: 17 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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