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Anti-Dystrobrevin alpha Polyclonal Antibody
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Catalog No. TMAB-05373
Anti-Dystrobrevin alpha Polyclonal Antibody is a Rabbit antibody targeting Dystrobrevin alpha. Anti-Dystrobrevin alpha Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Anti-Dystrobrevin alpha Polyclonal Antibody
Anti-Dystrobrevin alpha Polyclonal Antibody
😃Good
Catalog No. TMAB-05373
Anti-Dystrobrevin alpha Polyclonal Antibody is a Rabbit antibody targeting Dystrobrevin alpha. Anti-Dystrobrevin alpha Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Dystrobrevin alpha Polyclonal Antibody is a Rabbit antibody targeting Dystrobrevin alpha. Anti-Dystrobrevin alpha Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Dog,Horse) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cell projection, growth cone. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. |
| Tissue Specificity | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Dystrobrevin alpha belongs to the dystrobrevin subfamily of the dystrophin family. It is a component of the dystrophin associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha and beta dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin alpha may be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. Mutations in Dystrobrevin alpha are associated with left ventricular noncompaction with congenital heart defects. |
| Immunogen | KLH conjugated synthetic peptide: mouse Dystrobrevin alpha |
| Antigen Species | Mouse |
| Gene Name | DTNA |
| Gene ID | |
| Protein Name | Dystrobrevin alpha |
| Uniprot ID | |
| Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration . |
| Molecular Weight | Theoretical: 81 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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