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Anti-ACVR2A Polyclonal Antibody

Catalog No. TMAB-02268 Copy Product Info
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Anti-ACVR2A Polyclonal Antibody is a Rabbit antibody targeting ACVR2A. Anti-ACVR2A Polyclonal Antibody can be used in WB.

Anti-ACVR2A Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-02268

Anti-ACVR2A Polyclonal Antibody is a Rabbit antibody targeting ACVR2A. Anti-ACVR2A Polyclonal Antibody can be used in WB.

Anti-ACVR2A Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ACVR2A Polyclonal Antibody is a Rabbit antibody targeting ACVR2A. Anti-ACVR2A Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
Sample:
Lane 1: Ovary (Mouse) Lysate at 40 μg
Lane 2: Testis (Mouse) Lysate at 40 μg
Lane 3: Cerebrum (Mouse) Lysate at 40 μg
Lane 4: Testis (Rat) Lysate at 40 μg
Lane 5: Cerebrum (Rat) Lysate at 40 μg
Lane 6: Du145 (Human) Cell Lysate at 30 μg
Lane 7: SH-SY5Y (Human) Cell Lysate at 30 μg
Lane 8: U2os (Human) Cell Lysate at 30 μg
Primary: Anti-ACVR2A (TMAB-02268) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 68 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMembers of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse ACVR2A
Antigen Species
Mouse
Gene Name
ACVR2A
Gene ID
11480
Protein Name
Activin receptor type-2A
Uniprot ID
P27038
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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