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Anti-HMGB1 Polyclonal Antibody 3

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Catalog No. TMAB-07182

Anti-HMGB1 Polyclonal Antibody 3 is a Rabbit antibody targeting HMGB1. Anti-HMGB1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.

Anti-HMGB1 Polyclonal Antibody 3

Anti-HMGB1 Polyclonal Antibody 3

😃Good
Catalog No. TMAB-07182
Anti-HMGB1 Polyclonal Antibody 3 is a Rabbit antibody targeting HMGB1. Anti-HMGB1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HMGB1 Polyclonal Antibody 3 is a Rabbit antibody targeting HMGB1. Anti-HMGB1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse)
Application
Recommended Dose
IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Chromosome.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHigh Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagus nerve dependent mechanism, inhibits HMGB1 release in experimental disease models
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HMGB1
Antigen Species
Human
Gene Name
HMGB1
Gene ID
Protein Name
High mobility group protein B1
Uniprot ID
Function
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
Chemical Properties
Molecular WeightTheoretical: 25 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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