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Anti-SLIRP/C14orf156 Polyclonal Antibody
Catalog No. TMAB-12924 Copy Product Info
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Anti-SLIRP/C14orf156 Polyclonal Antibody is a Rabbit antibody targeting SLIRP/C14orf156. Anti-SLIRP/C14orf156 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-SLIRP/C14orf156 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-12924
Anti-SLIRP/C14orf156 Polyclonal Antibody is a Rabbit antibody targeting SLIRP/C14orf156. Anti-SLIRP/C14orf156 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-SLIRP/C14orf156 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SLIRP/C14orf156 Polyclonal Antibody is a Rabbit antibody targeting SLIRP/C14orf156. Anti-SLIRP/C14orf156 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Pig,Rabbit) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SLIRP/C14orf156) Polyclonal Antibody, Unconjugated (TMAB-12924) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SLIRP/C14orf156) Polyclonal Antibody, Unconjugated (TMAB-12924) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 3. Sample: Testis (Mouse) Lysate at 40 μg Primary: Anti-C14orf156 (TMAB-12924) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 12 kD Observed band size: 12 kD 4. Sample: Kidney (Mouse) Lysate at 40 μg Primary: Anti-SLIRP/C14orf156 (TMAB-12924) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 12 kD Observed band size: 11 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrial and Nuclear; Predominantly mitochondrial. |
| Tissue Specificity | Ubiquitously expressed, with highest level in heart, liver, skeletal muscle and testis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008] |
| Immunogen | KLH conjugated synthetic peptide: human SLIRP/C14orf156 |
| Antigen Species | Human |
| Gene Name | SLIRP |
| Gene ID | |
| Protein Name | SRA stem-loop-interacting RNA-binding protein, mitochondrial |
| Uniprot ID | |
| Function | RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation. |
| Molecular Weight | Theoretical: 12 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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