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Anti-RASA4 Polyclonal Antibody
Catalog No. TMAB-12104 Copy Product Info
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Anti-RASA4 Polyclonal Antibody is a Rabbit antibody targeting RASA4. Anti-RASA4 Polyclonal Antibody can be used in WB.
Anti-RASA4 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-12104
Anti-RASA4 Polyclonal Antibody is a Rabbit antibody targeting RASA4. Anti-RASA4 Polyclonal Antibody can be used in WB.
Anti-RASA4 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-RASA4 Polyclonal Antibody is a Rabbit antibody targeting RASA4. Anti-RASA4 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Sample: HepG2 Cell (Human) Lysate at 40 μg MCF-7 Cell (Human) Lysate at 40 μg Lovo Cell (Human) Lysate at 40 μg Primary: Anti-RASA4 (TMAB-12104) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kD Observed band size: 90 kD 2. Sample: spleen (Mouse) Lysate at 40 μg Primary: Anti-RASA4 (TMAB-12104) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kD Observed band size: 90 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm; cytosol. Cell membrane; peripheral membrane protein. Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane. |
| Tissue Specificity | Widely expressed. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human RASA4 |
| Antigen Species | Human |
| Gene Name | RASA4 |
| Gene ID | |
| Protein Name | Ras GTPase-activating protein 4 |
| Uniprot ID | |
| Function | Ca2+-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. |
| Molecular Weight | Theoretical: 90 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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