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Anti-TRIM41 Polyclonal Antibody

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Catalog No. TMAB-13783

Anti-TRIM41 Polyclonal Antibody is a Rabbit antibody targeting TRIM41. Anti-TRIM41 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-TRIM41 Polyclonal Antibody

Anti-TRIM41 Polyclonal Antibody

😃Good
Catalog No. TMAB-13783
Anti-TRIM41 Polyclonal Antibody is a Rabbit antibody targeting TRIM41. Anti-TRIM41 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TRIM41 Polyclonal Antibody is a Rabbit antibody targeting TRIM41. Anti-TRIM41 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Dog,Cow,Sheep)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus.
Tissue SpecificityExpressed in multiple tissues with the highest levels in heart and skeletal muscle.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundTripartite motif-containing protein 41 (TRIM41), also known as RINCK, is a 630 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Localized to both the nucleus and cytoplasm, TRIM41 associates with protein kinase C (PKC) through the C1A domain of PKC. Studies have shown that overexpression of TRIM41 reduces the levels of PKC in cells, whereas knockdown of TRIM41 leads to increased levels of PKC. Thus, it is hypothesized that TRIM41 plays a role in regulating PCK levels in cells, specifically through the ubiquitination of PKC. Four isoforms of TRIM41 exist as a result of alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TRIM41
Antigen Species
Human
Gene Name
TRIM41
Gene ID
90933
Protein Name
E3 ubiquitin-protein ligase TRIM41
Uniprot ID
Q8WV44
Function
Functions as an E3 ligase that catalyzes the ubiquitin-mediated degradation of protein kinase C.
Chemical Properties
Molecular WeightTheoretical: 72 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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