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Anti-MPP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-08967
Anti-MPP1 Polyclonal Antibody is a Rabbit antibody targeting MPP1. Anti-MPP1 Polyclonal Antibody can be used in WB.
Anti-MPP1 Polyclonal Antibody
Anti-MPP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-08967
Anti-MPP1 Polyclonal Antibody is a Rabbit antibody targeting MPP1. Anti-MPP1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MPP1 Polyclonal Antibody is a Rabbit antibody targeting MPP1. Anti-MPP1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Lipid-anchor. Cell projection, stereocilium (By similarity). Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non-myelin-forming Schwann cells. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The Kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual Kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events, including endocytosis and transcytosis. MPP1 (M-phase phosphoprotein 1), also known as KIF20B (kinesin family member 20B), MPHOSPH1 or KRMP1, is a 1,820 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one kinesin-motor domain. Expressed in kidney, brain, testis and ovary, MPP1 functions as a plus-end directed motor enzyme that interacts with Pin1 and is required for the completion of cytokinesis. MPP1, which exists as multiple alternatively spliced isoforms termed 1-5, is subject to post-translational phosphorylation, probably by ATM or ATR. |
| Immunogen | KLH conjugated synthetic peptide: human MPP1/EMP55 |
| Antigen Species | Human |
| Gene Name | MPP1 |
| Gene ID | |
| Protein Name | 55 kDa erythrocyte membrane protein |
| Uniprot ID | |
| Function | Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity). |
| Molecular Weight | Theoretical: 52 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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