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Anti-Wnt11 Polyclonal Antibody 2
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Catalog No. TMAB-14185
Anti-Wnt11 Polyclonal Antibody 2 is a Rabbit antibody targeting Wnt11. Anti-Wnt11 Polyclonal Antibody 2 can be used in WB.
Anti-Wnt11 Polyclonal Antibody 2
Anti-Wnt11 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-14185
Anti-Wnt11 Polyclonal Antibody 2 is a Rabbit antibody targeting Wnt11. Anti-Wnt11 Polyclonal Antibody 2 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Wnt11 Polyclonal Antibody 2 is a Rabbit antibody targeting Wnt11. Anti-Wnt11 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Human (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted; extracellular space; extracellular matrix. |
| Tissue Specificity | Expressed in fetal lung, kidney, adult heart, liver, skeletal muscle, and pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. The name Wnt denotes the relationship of this family to the Drosophila segment polarity gene ”wingless” and to its vertebrate ortholog, Int-1, a mouse proto-oncogene. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. The Wnt genes encode cysteine-rich putative glycoproteins which have features typical of secreted growth factors. Wnt-11 is expressed in the tips of ureteric buds and in the perichondrium, a stem cell-like layer that surrounds the future bones and directs their growth and regeneration. Wnt-11 activity is required for cells to undergo correct convergent extension movements during gastrulation. Human Wnt-11 is also expressed in the lung mesenchyme, the urorectal septum, the urogenital folds, the labioscrotal swellings, and the cortex of the adrenal gland. Unlike other Wnt family members, Wnt-11 is not expressed in the neuroepithelium of the central nervous system. Wnt-11, along with Wnt-8c, is ex-pressed in the posterior region of the chick embryo in the caudal paraxial mesoderm that underlies the prospective caudal neural plate. The gene which encodes Wnt-11 maps to human chromosome 11q13.5. |
| Immunogen | Recombinant Protein: mouse Wnt11 protein |
| Antigen Species | Mouse |
| Gene Name | WNT11 |
| Gene ID | |
| Protein Name | Protein Wnt-11 |
| Uniprot ID | |
| Function | Wnt11 is a non-canonical Wnt which is expressed in androgen-independent prostate cancer cell lines and prostate tumours. It is involved in development, including cardiac and gut development. |
| Molecular Weight | Theoretical: 39 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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